How Does Clonazepam Work?

Clonazepam, also well known by the brand name Klonopin, is a tranquiliser that is often indicated in the treatment of severe anxiety and panic disorder. This anti-anxiety treatment elevates levels of a natural calming chemical in the body, called GABA. GABA transmits signals throughout the nervous system and if there are insufficient levels of this chemical in the body, anxiety is more likely to happen. Heightened levels of anxiety can result in a panic attack. When taking this medication, more GABA is produced and this allows for a patient to remain in a tranquil state.

How Long Does It Take for Clonazepam to Work?

The effects of clonazepam occur quickly and most people experience relief from anxiety or insomnia within 20-60 minutes of taking a tablet. When used for insomnia, it should be taken immediately before bedtime, as a result of its fast-acting effects.

How Long Does Clonazepam Last?

In healthy adults, the effects of this treatment last about 8 to 12 hours. Therefore, clonazepam is usually taken in 2 to 3 divided doses per day. It reaches peak levels in the body within 1 to 4 hours and the bioavailability is approximately 90%. This means most of the medicine enters the blood circulation when ingested, giving these anxiety pills the ability to induce its therapeutic effects.

How Well Does Clonazepam Work?

When it comes to anti-anxiety medications, new patients often enquire what is clonazepam like, with regard to the treatment of anxiety disorders. Essentially, individuals using this medication for medical reasons may discover several benefits from its use.

• Often, people with anxiety disorders have difficulties with excessive feelings of nervousness on a daily basis. This medication has the ability to produce an overall calming effect which provides relief from anxiety.
• Effectively managing the symptoms of an anxiety disorder with medication, psychotherapy or a combination of both can uplift a patient's quality of life. This anti-anxiety therapeutic can be beneficial in the treatment of the following conditions:

• A clinical trial was conducted to assess the use of clonazepam in the treatment of panic disorder. The safety, efficacy, dosing aspects and discontinuation of treatment were analysed amongst 430 patients with panic disorder. They randomly received an inactive placebo treatment or a fixed clonazepam dosage of 0.5 mg, 1 mg, 2 mg, 3 mg and 4 mg, to take on a daily basis.
• For three weeks, patients increased their doses gradually until they had reached their required daily dosage. Thereafter, they took their daily doses for 6 weeks during the dose maintenance phase of the study. Finally, they slowly tapered off their dosages during a 7-week discontinuation phase.
• At the end of the 6-week dose maintenance phase, the four higher clonazepam dosages were clearly more effective than the 0.5 mg dose and the placebo as well. An assessment tool called the William's test was used to determine results. It showed that the minimum effective dose was 1 mg per day.
• Daily doses of 1 mg or higher were equally effective at reducing the number of panic attacks experienced by patients. In the tapering phase of the study, patients in all groups tolerated the discontinuation of clonazepam anxiety medication, with little or no clonazepam side effects. Daily doses of clonazepam 2 mg (or 1 mg dosages) provided the optimal balance of tolerability and therapeutic effects.

How Long Does Clonazepam Stay In Your System?

This tranquiliser has a relatively long elimination half-life. On average, it takes approximately 30 to 40 hours for half the medicine to be completely removed from the body. Like all medicines, however, the half-life can vary according to the following factors:

• Age - in general, the younger a person is, the faster they will process clonazepam. Younger people usually have a faster metabolism than older people. Having said that, some senior individuals can be healthier than younger people, so age is not always a significant factor.
• Body mass index (BMI) - patients with a higher BMI tend to have a slower metabolism than those with a lower BMI. For this reason, it will usually take longer for the medication to be eliminated by a person who has a higher BMI.
• Dosage - a large dose of this medicine will take longer to be removed from the body than a smaller dose. Typically, the larger the dose, the longer the half-life.
• Frequency and duration of use - if clonazepam tablets are used frequently and on a long-term basis, this therapeutic may accumulate in the body. Therefore, a person who takes more of these anxiety pills, and more regularly, will take longer to eliminate it than one who takes a single dosage.
• Overall health - a healthy individual will be able to remove this medication from their system at a much faster rate. In contrast, an unhealthy person will have a slower metabolism and will therefore eliminate the medicine at a slower rate.

The elimination time of clonazepam can vary considerably from one person to another. Depending on the factors listed above, this medication usually stays in a person's system between 5 and 14 days. You can buy anti-anxiety medication, like Klonopin, online and effectively manage the symptoms of anxiety, panic or insomnia. Our pharmaceuticals are sourced from leading manufacturers and customer care is available at all hours.

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CONTENT CHECKED: 09th AUG 2022
NEXT CHECK DUE: AUG 2023