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Nitrazepam Side Effects

Nitrazepam Side Effects

Along with its therapeutic effects, this medication can cause mild adverse reactions in a small percentage of people. The following table shows some of the more common nitrazepam side effects and what to do if you experience them:

Up to 1 in 10 people experience this What to do if you experience this adverse effect
Feeling light-headed or daytime sleepiness Avoid driving a vehicle or operating machinery if you experience daytime sleepiness or light-headedness. This side effect tends to improve as you get used to the medicine.
Unsteadiness or reduced co-ordination Ensure that you get plenty of rest and avoid the use of alcohol if you experience this side effect.
Muscle weakness Drink 2 to 3 litres of fluid throughout the day to prevent muscle weakness caused by dehydration.
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Nitrazepam Effects

This medication is a sedative-hypnotic treatment that produces a calm and sleep-inducing effect. It relaxes muscles and relieves feelings of nervousness, restlessness and anxiety. This makes it effective in the treatment of insomnia. This condition involves poor quality or quantity of sleep, despite having enough time to achieve restful sleep. Common symptoms of insomnia include:

  • Trouble falling asleep
  • Frequent nighttime awakenings
  • Early-morning awakenings
  • Not feeling well-rested in the morning
  • Feelings of irritability or anxiety

When it comes to treating insomnia, people with this condition are usually looking for an effective sleep aid so they can get the sleep relief they need. What is nitrazepam and how does nitrazepam work are common questions posed by patients all over, and useful information resources like this article, prove useful in affording clarity. Also marketed under the brand name Mogadon, nitrazepam is a hypnotic (sleep-inducing) medication that belongs to the benzodiazepine class. It has been available for medical use since 1965 and is indicated for the treatment of severe anxiety and insomnia.

This medication works by activating the release of a neurotransmitter called GABA. This neurotransmitter transmits chemical messages and helps reduce or inhibit the activity of overexcited nerve cells. GABA plays an essential role in how the body responds to anxiety and acts as a natural calming agent. Unusually low levels of this chemical messenger have been linked to sleep disorders like insomnia.

By enhancing GABA levels, nitrazepam creates a relaxing effect that is beneficial in the treatment of sleep onset insomnia. This type of insomnia is characterised by difficulty transitioning from a state of wakefulness to the initial stages of sleep.

The majority of people with sleep onset insomnia find it difficult to fall asleep within 30 minutes after the lights have been switched off. An inability to fall asleep generally results in reduced total sleep time which comes with negative daytime consequences like fatigue, impaired cognition and reduced alertness. This medication can, however, be used to treat sleep onset insomnia so a full night's rest can be achieved.

In addition to the time it takes to fall asleep, this medication can help reduce or prevent nighttime awakenings. Waking up at least once during the night with difficulty returning to sleep is known as middle-of-the-night (MOTN) insomnia. In sleep studies, nitrazepam 5 mg and 10 mg doses have been shown to significantly reduce nighttime awakenings and the amount of time spent awake after sleep onset.

How Sleeping Tablets Work

Is Nitrazepam Dangerous?

In clinical research, this medication has been shown to be safe and effective, particularly when patients adhere to usage and dosage guidelines. A clinical trial was conducted to evaluate the safety and efficacy of this medication for the long-term treatment of chronic insomnia. Altogether, 26 patients with insomnia were treated with nitrazepam tablets for a period of 1 to 12 weeks. Another group of 11 healthy volunteers without insomnia were also treated with this medication so researchers could compare the difference among groups.

Specific measures were used to determine how the medication affected the patients physically. The results were also determined by using a subjective estimate by participants of the effects of treatment as well as nitrazepam side effects. The study found that the absorption, metabolism and excretion of the medication were similar among both groups. Patients in both groups rated the hypnotic effect of the medication as mostly good or satisfactory. The efficacy remained consistent during long-term treatment and only a few mild nitrazepam side effects were experienced by patients.

Sleeping Tablets Side Effects

Nitrazepam Addiction

This medication may become habit-forming if it is not used as recommended. In general, it should not be taken on consecutive nights for longer than four weeks. Also, the maximum recommended dose in a 24-hour period is one nitrazepam 10 mg tablet. The lowest effective dose should be used and experts usually recommend taking this medication on an intermittent basis if possible. For example, only take a tablet 2 or 3 nights a week, instead of every night.

Sleep hygiene techniques should be prioritised to improve overall sleep quality. Healthy habits like maintaining a regular sleep schedule, avoiding daytime naps and having a quiet, comfortable bedroom can help improve overall sleep.

Zolpidem Side Effects

Nitrazepam Withdrawal Symptoms

Although this medication is highly effective at treating insomnia, some people may develop a psychological or physical dependence to it. Taking it every night for longer than the recommended four weeks and at higher doses can lead to an increased risk of tolerance and dependence. The following factors increase the likelihood of withdrawal symptoms at the end of treatment:

  • Whether you are currently using more than one sedating medication
  • Whether you are discontinuing more than one treatment at a time

If you decide to discontinue treatment, withdrawal symptoms may happen, particularly if the nitrazepam dosage is not reduced gradually. Withdrawal symptoms include headaches, nervousness, irritability and mood changes. In the average person, these withdrawal symptoms will only last about 1-2 weeks. Because this medication has a relatively long half-life, withdrawal symptoms may not occur until about the fourth day after discontinuing use. In order to reduce the likelihood of these symptoms, the dose should be decreased gradually over the course of a few days or weeks.

You can buy sleeping tablets to effectively treat insomnia. Nitrazepam sleeping pills are recommended for the short-term treatment of sleeplessness, which is severe and causing a considerable amount of distress. When used as recommended, this medication is considered to be a safe and effective hypnotic. Simply visit our online pharmacy to buy nitrazepam tablets today and regain a healthy sleep schedule.

Don't forget, at, as well as strong sleeping pills, you can also buy a wide selection of anxiety medication and painkillers without a doctor's prescription!




Quickly establishing herself as a content writer Sarah found herself drawn to the medical industry – specifically in the field of Cognitive Behavioural Therapy (CBT-I), and sleep aids for insomnia. Sarah brings a wealth of experience, expertise and enthusiasm and will no doubt keep our readers absorbed with her insightful and thoughtful blogs written especially for

Amy White – May 12, 2021
Superb blog Sarah I am thankful for the invaluable information you shared in your article. Keep them coming Thank You Amy White

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